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Patient Experience: ‘After accidentally taking 12.5mg instead of 7.5mg of Tirzepatide, I had to restart at 2.5mg two weeks later—and even that felt stronger than before

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Consider antihistamine pretreatment For users who consistently experience mild injection site reactions despite proper technique and rotation, taking a non-drowsy antihistamine 30 to 60 minutes before injection can reduce or prevent histamine-mediated reactions